Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309624 | 0.86 | LMNA (0.65) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2947221 | 0.83 | LMNA (0.43) | LMNATSHRALDH1A1GPR84PPARG | |
| SCHEMBL28338753 | 0.83 | TSHR (0.40) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL2182362 | 0.81 | LMNA (0.48) | LMNATSHRNFKB1PMP22MAPT | |
| SCHEMBL27324519 | 0.81 | LMNA (0.52) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL28798937 | 0.81 | LMNA (0.52) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL769184 | 0.79 | TSHR (0.47) | LMNATSHRALDH1A1GPR84PPARG | |
| SCHEMBL14809726 | 0.79 | LMNA (0.70) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL14809980 | 0.79 | LMNA (0.70) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL3505211 | 0.79 | LMNA (0.70) | LMNATSHRNFKB1PMP22ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060039980-A1 | Process of preparing a biodegradable polymer using an enzyme catalyst and a biodegradable polymer prepared through the process | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-02-23 | — | — | US | claimed |
| US-20140276995-A1 | 4D Dynamically Contouring Mesh and Sutures | NOVO IP, LLC | 2014-09-18 | — | — | US | disclosed |
| US-20130090521-A1 | TIMED-RELEASE TENSIONED OR COMPRESSED FIBERS | NOVO CONTOUR, INC. (US) | 2013-04-11 | — | — | US | disclosed |
| US-7642075-B2 | Process of preparing a biodegradable polymer using an enzyme catalyst and a biodegradable polymer prepared through the process | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2010-01-05 | — | — | US | disclosed |
| US-20060039980-A1 | Process of preparing a biodegradable polymer using an enzyme catalyst and a biodegradable polymer prepared through the process | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-02-23 | — | — | US | disclosed |
| US-5162414-A | Polyester fiber web embedded in matrix of flowable phenolic prepolymer and interfacial solvent for polyester; flame retardant | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1992-11-10 | — | — | US | disclosed |
| US-4394338-A | Production of elongated fiber-reinforced composite articles | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1983-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060039980-A1 | Process of preparing a biodegradable polymer using an enzyme catalyst and a biodegradable polymer prepared through the process | HPD, DERA, ADH1C | LMNA 2352/4885TSHR 3020/4885NFKB1 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.