Phosphoric Acid

Phosphoric Acid

SCHEMBL13730179

CC(N)CCc1cc(F)c(F)cc1F.O=P(O)(O)O

nearest known ligand 0.46

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP4 known ✓ P27487 13/20 0.46
KCNH2 known ✓ Q12809 1/20 0.34
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
DPP8 Q6V1X1 3/20 0.35
DPP9 Q86TI2 3/20 0.35
FAP Q12884 2/20 0.35
DPP7 Q9UHL4 2/20 0.35
CYP3A4 P08684 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL14128619 0.98 DPP4 (0.45) DPP4ALDH1A1TDP1SLC6A2SLC6A4
SCHEMBL4697922 0.89 DPP4 (0.55) DPP4SLC6A2SLC6A4SLC6A3DPP8
Hydrochloric Acid SCHEMBL13730064 0.88 DPP4 (0.53) DPP4SLC6A2SLC6A4SLC6A3DPP8
Trifluoroacetic Acid SCHEMBL3134971 0.83 DPP4 (0.42) DPP4SLC6A2SLC6A4SLC6A3DPP8
Adipic Acid SCHEMBL13729711 0.81 GABRP (0.44) DPP4ALDH1A1DPP8DPP9FAP
SCHEMBL7140782 0.74 TYR (0.52) DPP4SLC6A4HDAC1HDAC8
Gentisic Acid SCHEMBL13729892 0.74 CA1 (0.49) ALDH1A1TDP1CYP3A4
SCHEMBL15155703 0.74 GABRR1 (0.45) DPP4HDAC1HDAC8
SCHEMBL15091259 0.74 DPP4 (0.42) DPP4SLC6A2SLC6A4SLC6A3
Phosphoric Acid SCHEMBL13730837 0.73 DPP4 (0.50) DPP4DPP8DPP9DPP7CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2681220-A2 NOVEL SALTS OF DPP-IV INHIBITOR Cadila Healthcare Limited (IN) 2014-01-08 EP disclosed
WO-2012147092-A2 NOVEL SALTS OF DPP-IV INHIBITOR CADILA HEALTHCARE LIMITED (IN) 2012-11-01 WO disclosed