Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506378 | 0.84 | MEN1 (0.50) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20256401 | 0.84 | MEN1 (0.50) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13040779 | 0.82 | NLRP3 (0.61) | ALDH1A1HPGDSMN1; SMN2NLRP3KDM4E | |
| SCHEMBL31350565 | 0.76 | HTT (0.46) | ALDH1A1HPGDSMN1; SMN2KDM4ELMNA | |
| SCHEMBL20256135 | 0.72 | ADORA1 (0.49) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13040787 | 0.71 | NLRP3 (0.57) | MEN1KMT2ASMN1; SMN2NLRP3KDM4E | |
| SCHEMBL19876625 | 0.71 | DHFR (0.71) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29487320 | 0.70 | DCPS (0.63) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1620592 | 0.70 | DCPS (0.63) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3325825 | 0.69 | ACHE (0.46) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |