Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 12/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.45 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21497120 | 0.78 | PGR (0.43) | HSD17B10CYP3A4PGRNR3C1NR3C2 | |
| Water SCHEMBL7721550 | 0.76 | CYP3A4 (0.94) | ALOX15HSD17B10CYP3A4BRD4MEN1 | |
| SCHEMBL3141614 | 0.75 | CYP3A4 (0.61) | ALOX15HSD17B10CYP3A4BRD4MEN1 | |
| SCHEMBL3137674 | 0.75 | CYP3A4 (0.61) | ALOX15HSD17B10CYP3A4BRD4MEN1 | |
| SCHEMBL23924225 | 0.74 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4BRD4MEN1 | |
| SCHEMBL29549758 | 0.74 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4BRD4MEN1 | |
| SCHEMBL29365557 | 0.74 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4BRD4MEN1 | |
| SCHEMBL105866 | 0.74 | CYP3A4 (1.00) | ALOX15HSD17B10CYP3A4BRD4MEN1 | |
| SCHEMBL5843660 | 0.74 | ALOX15 (0.65) | ALOX15HSD17B10CYP3A4PGRBRD4 | |
| SCHEMBL31117797 | 0.73 | MAOA (0.47) | CYP3A4PGRNR3C1NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-02 | — | — | US | claimed |
| EP-1768971-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006007896-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | WO | claimed |
| US-7641702-B2 | O-Aminophenol derivatives and colorants containing said compounds | WELLA AG (DE) | 2010-01-05 | — | — | US | disclosed |
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-02 | — | — | US | disclosed |
| EP-1768971-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006007896-A1 | NOVEL O-AMINOPHENOL DERIVATIVES AND COLORANTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080235882-A1 | Novel O-Aminophenol Derivatives and Colorants Containing Said Compounds | CBR3, KRT18, F12 | ALOX15 3757/4885HSD17B10 2013/4885CYP3A4 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.