SCHEMBL31353086

SCHEMBL31353086

N#Cc1cc(Br)cc([N+](=O)[O-])c1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 5/20 0.56
GPR35 Q9HC97 2/20 0.51
MAPT P10636 3/20 0.41
GRIA1 P42261 2/20 0.41
GRIA2 P42262 2/20 0.41
GRIA3 P42263 2/20 0.41
GRIA4 P48058 2/20 0.41
ALOX15 P16050 2/20 0.41
GRM6 O15303 1/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
POLB P06746 1/20 0.41
CYP2C9 P11712 1/20 0.41
APEX1 P27695 1/20 0.41
BLM P54132 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31419521 0.82 VCAM1 (0.64) VCAM1GPR35MAPTGRIA1GRIA2
SCHEMBL11504122 0.82 VCAM1 (0.64) VCAM1GPR35MAPTGRIA1GRIA2
SCHEMBL11521290 0.81 TSHR (0.55) VCAM1GPR35ALOX15CYP1A2HPGD
SCHEMBL31353089 0.81 GPR35 (0.52) VCAM1GPR35MAPTGRIA1GRIA2
SCHEMBL4665872 0.81 VCAM1 (0.58) VCAM1GPR35MAPTGRIA1GRIA2
SCHEMBL1343512 0.79 GPR35 (0.51) VCAM1GPR35MAPTGRIA1GRIA2
SCHEMBL3814947 0.79 ERN1 (0.54) VCAM1GPR35MAPTGRIA1GRIA2
SCHEMBL31374335 0.79 GPR35 (0.51) VCAM1GPR35MAPTGRIA1GRIA2
SCHEMBL11571620 0.77 VCAM1 (0.58) VCAM1GPR35MAPTGRIA1GRIA2
SCHEMBL25314994 0.76 TSHR (0.48) VCAM1GPR35ALOX15HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119490423-A Method for preparing 2-fluoro-3-aminobenzoic acid and ester compound thereof 沈阳中化农药化工研发有限公司 2025-02-21 CN disclosed
CN-119490424-A Preparation method of 2-fluoro-3-aminobenzoic acid and ester compound 沈阳中化农药化工研发有限公司 2025-02-21 CN disclosed
CN-119490421-A Method for synthesizing 2-fluoro-3-aminobenzoic acid and ester compound thereof 沈阳中化农药化工研发有限公司 2025-02-21 CN disclosed
WO-2025036387-A1 PREPARATION METHOD FOR 2-FLUORO-3-AMINOBENZOIC ACID AND ESTER COMPOUNDS 沈阳中化农药化工研发有限公司 2025-02-20 WO disclosed
WO-2025036384-A1 METHOD FOR PREPARING 2-CHLORO-3-AMINOBENZOIC ACID AND ESTER COMPOUND THEREOF 沈阳中化农药化工研发有限公司 2025-02-20 WO disclosed
CN-119143752-A Aminoquinoline derivative, pharmaceutical composition containing same, preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2024-12-17 CN disclosed