SCHEMBL3814947

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4144580	0.81	ERN1 (0.69)	ERN1GPR35MAPTMEN1ALDH1A1
	SCHEMBL28490634	0.81	VCAM1 (0.58)	GPR35VCAM1CTSBMAPTMEN1
	SCHEMBL31353089	0.81	GPR35 (0.52)	ERN1GPR35VCAM1CTSBMAPT
	SCHEMBL31374335	0.79	GPR35 (0.51)	ERN1GPR35VCAM1MAPTMEN1
	SCHEMBL31353086	0.79	VCAM1 (0.56)	ERN1GPR35VCAM1MAPTMEN1
	SCHEMBL16096964	0.79	VCAM1 (0.60)	GPR35VCAM1CTSBMAPTMEN1
	SCHEMBL1343512	0.79	GPR35 (0.51)	ERN1GPR35VCAM1MAPTMEN1
	SCHEMBL25171478	0.79	GPR35 (0.48)	ERN1GPR35VCAM1MAPTMEN1
	SCHEMBL31220231	0.79	GPR35 (0.48)	ERN1GPR35VCAM1MAPTMEN1
	SCHEMBL1515777	0.77	XDH (0.63)	ERN1VCAM1CTSBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.