SCHEMBL4665872

SCHEMBL4665872

N#Cc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 5/20 0.58
XDH P47989 1/20 0.50
GPR35 Q9HC97 3/20 0.47
ALDH1A1 P00352 4/20 0.47
LMNA P02545 1/20 0.43
MAPT P10636 3/20 0.42
GRIA1 P42261 2/20 0.42
GRIA2 P42262 2/20 0.42
GRIA3 P42263 2/20 0.42
GRIA4 P48058 2/20 0.42
CYP1A2 P05177 2/20 0.42
ALOX15 P16050 2/20 0.42
GRM6 O15303 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP2C9 P11712 2/20 0.42
HPGD P15428 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
TTR P02766 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14637726 0.94 VCAM1 (0.66) VCAM1XDHGPR35ALDH1A1LMNA
SCHEMBL11871225 0.89 VCAM1 (0.65) VCAM1XDHGPR35ALDH1A1LMNA
SCHEMBL22322115 0.87 VCAM1 (0.46) VCAM1XDHGPR35ALDH1A1LMNA
SCHEMBL6431969 0.84 ALDH1A1 (0.64) VCAM1XDHGPR35ALDH1A1LMNA
SCHEMBL11504122 0.84 VCAM1 (0.64) VCAM1GPR35ALDH1A1MAPTGRIA1
SCHEMBL31419521 0.84 VCAM1 (0.64) VCAM1GPR35ALDH1A1MAPTGRIA1
SCHEMBL31353086 0.81 VCAM1 (0.56) VCAM1GPR35ALDH1A1MAPTGRIA1
SCHEMBL6436847 0.81 VCAM1 (0.56) VCAM1XDHGPR35ALDH1A1LMNA
SCHEMBL213849 0.80 ALDH1A1 (0.62) VCAM1GPR35ALDH1A1MAPTCYP1A2
SCHEMBL10818750 0.80 ALDH1A1 (0.62) VCAM1GPR35ALDH1A1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4441112-A1 METHOD OF UNDERWATER BONDING Henkel AG & Co. KGaA (DE) 2024-10-09 EP claimed
US-20240318052-A1 METHOD OF UNDERWATER BONDING HENKEL AG & CO KGAA (DE) 2024-09-26 US claimed
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
CN-116410114-B 4-nitrobenzene sulfur chlorine amino protecting group and preparation method thereof 南开大学 2024-02-27 CN claimed
CN-116410114-A 4-nitrobenzene sulfur chlorine amino protecting group and preparation method thereof 南开大学 2023-07-11 CN claimed
WO-2023099777-A1 METHOD OF UNDERWATER BONDING Henkel IP & Holding GmbH (DE) 2023-06-08 WO claimed
US-11555135-B2 Cyanoacrylate compositions HENKEL AG & CO. KGAA (DE) 2023-01-17 US claimed
CN-111278878-B Cyanoacrylate compositions 汉高股份有限及两合公司 2022-08-26 CN claimed
CN-110741055-B Cyanoacrylate compositions 汉高知识产权控股有限责任公司 2022-04-29 CN claimed
EP-3619275-B1 CYANOACRYLATE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2022-02-23 EP claimed
WO-2018202384-A1 CYANOACRYLATE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2018-11-08 WO claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
CN-106977424-A A kind of preparation method of the diaminobenzene formonitrile HCN of 4 chlorine of Lodoxamide intermediate 3,5 山东绅联药业有限公司 2017-07-25 CN claimed
US-9120957-B2 Cyanoacrylate compositions Henkel IP & Holding GmbH (DE) 2015-09-01 US claimed
US-20140124137-A1 CYANOACRYLATE COMPOSITIONS Henkel lP & Holding GmbH (DE) 2014-05-08 US claimed
EP-0594317-B1 Cyanoacrylate adhesives with improved cured thermal properties utilizing substituted aromatic additive LOCTITE CORP (US) 1997-09-03 EP claimed
EP-0594317-A1 Cyanoacrylate adhesives with improved cured thermal properties utilizing substituted aromatic additive LOCTITE CORPORATION (US) 1994-04-27 EP claimed
US-5288794-A Benzene compounds substituted with two or more electron withdrawing groups and one or more leaving groups delay onset of thermal decomposition LOCTITE CORPORATION (US) 1994-02-22 US claimed