Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135404 | 1.00 | ESR1 (0.39) | ESR1HTTALDH1A1TDP1KDM4E | |
| SCHEMBL3144475 | 0.95 | ESR1 (0.41) | ESR1HTTALDH1A1TDP1KDM4E | |
| SCHEMBL17791884 | 0.84 | HMGCR (0.41) | ESR1HTTTDP1SMN1; SMN2TP53 | |
| SCHEMBL3139330 | 0.84 | ESR1 (0.38) | ESR1HTTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL13374133 | 0.84 | ESR1 (0.38) | ESR1HTTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL13475561 | 0.82 | ESR1 (0.49) | ESR1HTTTDP1SMN1; SMN2TP53 | |
| SCHEMBL13374134 | 0.77 | ESR1 (0.36) | ESR1HTTSMN1; SMN2MAPTTLR8 | |
| SCHEMBL4430873 | 0.75 | LMNA (0.41) | HTTALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL8056947 | 0.75 | HTT (0.38) | ESR1HTTALDH1A1TDP1KDM4E | |
| SCHEMBL8056949 | 0.75 | HTT (0.38) | ESR1HTTALDH1A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288542-B2 | Noble ruthenium-type sensitizer and method of preparing the same | DONGJIN SEMICHEM CO., LTD. (KR) | 2012-10-16 | — | — | US | disclosed |
| US-8288542-B2 | Noble ruthenium-type sensitizer and method of preparing the same | DONGJIN SEMICHEM CO., LTD. (KR) | 2012-10-16 | — | — | US | disclosed |
| US-8288542-B2 | Noble ruthenium-type sensitizer and method of preparing the same | DONGJIN SEMICHEM CO., LTD. (KR) | 2012-10-16 | — | — | US | disclosed |
| US-20100071763-A1 | NOBLE RUTHENIUM-TYPE SENSITIZER AND METHOD OF PREPARING THE SAME | DONGJIN SEMICHEM CO., LTD. (KR) | 2010-03-25 | — | — | US | disclosed |
| US-20100071763-A1 | NOBLE RUTHENIUM-TYPE SENSITIZER AND METHOD OF PREPARING THE SAME | DONGJIN SEMICHEM CO., LTD. (KR) | 2010-03-25 | — | — | US | disclosed |
| US-20100071763-A1 | NOBLE RUTHENIUM-TYPE SENSITIZER AND METHOD OF PREPARING THE SAME | DONGJIN SEMICHEM CO., LTD. (KR) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100071763-A1 | NOBLE RUTHENIUM-TYPE SENSITIZER AND METHOD OF PREPARING THE SAME | MSH6, CRY1, MKI67 | ESR1 2212/4885HTT 4620/4885ALDH1A1 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.