SCHEMBL3144475

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3135401	0.95	ESR1 (0.39)	ESR1ALDH1A1TDP1KDM4ETSHR
	SCHEMBL3135404	0.95	ESR1 (0.39)	ESR1ALDH1A1TDP1KDM4ETSHR
	SCHEMBL13475561	0.86	ESR1 (0.49)	ESR1TDP1HTTSMN1; SMN2TP53
	SCHEMBL17791884	0.82	HMGCR (0.41)	ESR1TDP1HTTSMN1; SMN2TP53
	SCHEMBL4430873	0.79	LMNA (0.41)	ALDH1A1TDP1KDM4ETSHRHTT
	SCHEMBL13374133	0.78	ESR1 (0.38)	ESR1ALDH1A1TDP1HTTSMN1; SMN2
	SCHEMBL3139330	0.78	ESR1 (0.38)	ESR1ALDH1A1TDP1HTTSMN1; SMN2
	SCHEMBL5451418	0.78	FDPS (0.51)	ESR1ALDH1A1TDP1TSHRHTT
	SCHEMBL1852272	0.76	ALDH1A1 (0.69)	ALDH1A1KDM4EHTTSMN1; SMN2HPGD
	SCHEMBL28639293	0.74	ALDH1A1 (0.47)	ALDH1A1HTTSMN1; SMN2HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.