SCHEMBL313548

SCHEMBL313548

O=S(=O)(O)c1ccc(Br)cc1.[NaH]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
CA2 P00918 5/20 0.54
TSHR P16473 2/20 0.54
ALDH1A1 P00352 1/20 0.54
NT5E P21589 1/20 0.54
CA1 P00915 3/20 0.54
MMP2 P08253 2/20 0.54
MMP1 P03956 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.52
PLCG1 P19174 1/20 0.52
F2 P00734 2/20 0.48
PRSS1 P07477 2/20 0.48
PRSS2 P07478 2/20 0.48
PRSS3 P35030 2/20 0.48
CA12 O43570 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5549033 0.97 LMNA (0.59) LMNAMEN1KMT2ACA2TSHR
SCHEMBL19670 0.97 LMNA (0.59) LMNAMEN1KMT2ACA2TSHR
SCHEMBL8714156 0.95 LMNA (0.56) LMNAMEN1KMT2ACA2TSHR
Methane SCHEMBL7758417 0.95 LMNA (0.56) LMNAMEN1KMT2ACA2TSHR
SCHEMBL6915202 0.95 LMNA (0.56) LMNAMEN1KMT2ACA2TSHR
SCHEMBL6914844 0.95 LMNA (0.56) LMNAMEN1KMT2ACA2TSHR
SCHEMBL6918769 0.95 LMNA (0.56) LMNAMEN1KMT2ACA2TSHR
SCHEMBL6915968 0.95 LMNA (0.56) LMNAMEN1KMT2ACA2TSHR
SCHEMBL6914848 0.95 LMNA (0.56) LMNAMEN1KMT2ACA2TSHR
SCHEMBL6917226 0.95 LMNA (0.56) LMNAMEN1KMT2ACA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325091-A Side chain type sulfonated polyarylethersulfone (ketone) and preparation method and application thereof 吉林化工学院 2024-07-12 CN claimed
CN-116375907-A Method for producing sugammadex 默沙东有限责任公司 2023-07-04 CN claimed
CN-111777534-B Alkynyl sulfone compound and preparation method and application thereof 南京林业大学 2022-04-12 CN claimed
CN-110526847-B Synthesis method of N-aryl sulfuryl sulfoxide imine 成都理工大学 2021-01-19 CN claimed
US-7008646-B2 Cubic liquid crystalline compositions and methods for their preparation CHILDREN'S HOSPITAL RESEARCH FOUNDATION 2006-03-07 US claimed
EP-0897808-B1 Recording sheets and ink jet printing processes therewith XEROX CORP (US) 2004-06-16 EP claimed
EP-1361865-A2 CUBIC LIQUID CRYSTALLINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION THE PROCTER & GAMBLE COMPANY (US) 2003-11-19 EP claimed
US-20020160040-A1 Cubic liquid crystalline compositions and methods for their preparation CHILDREN'S HOSPITAL RESEARCH FOUNDATION 2002-10-31 US claimed
WO-2002066014-A2 CUBIC LIQUID CRYSTALLINE COMPOSITIONS AND METHODS FOR THEIR PREPARATION THE PROCTER & GAMBLE COMPANY (US) 2002-08-29 WO claimed
US-6117527-A RECORDING SHEET COMPRISING SUBSTRATE HAVING IMAGE-RECEIVING COATING ON SURFACE COMPRISING BINDER POLYMER AND SELECTED ADDITIVE; HIGH QUALITY IMAGES WITH REDUCED OR NO HAZE XEROX CORPORATION (US) 2000-09-12 US claimed
EP-0897808-A1 Recording sheets and ink jet printing processes therewith Xerox Corporation (US) 1999-02-24 EP claimed
US-12564546-B2 Self-tanning compositions containing an aromatic sulfonate and methods thereof KAO CORPORATION (JP) 2026-03-03 US disclosed
CN-118325091-A Side chain type sulfonated polyarylethersulfone (ketone) and preparation method and application thereof 吉林化工学院 2024-07-12 CN disclosed
CN-117926289-A Method for electrochemically synthesizing N-sulfoamidine derivatives under mild condition 湘潭大学 2024-04-26 CN disclosed
CN-115403494-B Method for synthesizing beta-hydroxy sulfone derivative by oxygen-initiated olefin double-functionalization under mild condition 湘潭大学 2024-01-02 CN disclosed
US-6117527-A RECORDING SHEET COMPRISING SUBSTRATE HAVING IMAGE-RECEIVING COATING ON SURFACE COMPRISING BINDER POLYMER AND SELECTED ADDITIVE; HIGH QUALITY IMAGES WITH REDUCED OR NO HAZE XEROX CORPORATION (US) 2000-09-12 US disclosed
EP-0897808-A1 Recording sheets and ink jet printing processes therewith Xerox Corporation (US) 1999-02-24 EP disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
US-5043510-A Aqueous alkylation process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020160040-A1 Cubic liquid crystalline compositions and methods for their preparation SKP1, CCNB1, CRYAA LMNA 321/4885MEN1 1187/4885KMT2A 4643/4885
US-12564546-B2 Self-tanning compositions containing an aromatic sulfonate and methods thereof CUTA, TYR, TREH LMNA 645/4885MEN1 4510/4885KMT2A 1333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.