Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PON1 | P27169 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312190 | 0.89 | MAPT (0.31) | MAPT | |
| SCHEMBL29471001 | 0.80 | ALDH1A1 (0.45) | CYP1A2CYP2C19ALDH1A1NPC1PLA2G1B | |
| SCHEMBL311978 | 0.80 | ALDH1A1 (0.45) | CYP1A2CYP2C19ALDH1A1NPC1PLA2G1B | |
| SCHEMBL14627275 | 0.79 | MAPT (0.33) | NPC1RAB9AMAPT | |
| SCHEMBL18315273 | 0.78 | ALDH1A1 (0.44) | CYP1A2CYP2C19ALDH1A1NPC1PLA2G1B | |
| Lithium SCHEMBL18315275 | 0.78 | ALDH1A1 (0.44) | CYP1A2CYP2C19ALDH1A1NPC1PLA2G1B | |
| SCHEMBL3890954 | 0.78 | ALDH1A1 (0.36) | CYP1A2CYP2C19ALDH1A1NPC1PLA2G1B | |
| SCHEMBL27500824 | 0.75 | ALDH1A1 (0.44) | CYP1A2CYP2C19ALDH1A1NPC1PLA2G1B | |
| SCHEMBL27481535 | 0.75 | ALDH1A1 (0.44) | CYP1A2CYP2C19ALDH1A1NPC1PLA2G1B | |
| SCHEMBL1480183 | 0.73 | NPC1 (0.41) | CYP1A2CYP2C19ALDH1A1NPC1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130237719-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | FINA TECHNOLOGY, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130237719-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | FINA TECHNOLOGY, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-8093418-B2 | Metallocenes; for production of ethylene/propylene homo-/copolymers | FINA TECHNOLOGY, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093418-B2 | Metallocenes; for production of ethylene/propylene homo-/copolymers | FINA TECHNOLOGY, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093418-B2 | Metallocenes; for production of ethylene/propylene homo-/copolymers | FINA TECHNOLOGY, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-7605294-B2 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7605294-B2 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-20080026935-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | FINA TECHNOLOGY, INC. (US) | 2008-01-31 | — | — | US | disclosed |
| WO-2007022244-A2 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007022244-A2 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070043183-A1 | Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins | FINA TECHNOLOGY, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070043183-A1 | Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins | FINA TECHNOLOGY, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070043183-A1 | Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins | FINA TECHNOLOGY, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-7094938-B1 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2006-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237719-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | SFN, FANCF, B2M | CYP1A2 713/4885CYP2C19 1035/4885PON1 2435/4885 |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | TFDP2, ZKSCAN2, MDM4 | CYP1A2 656/4885CYP2C19 741/4885PON1 4395/4885 |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | PYM1, SFN, FANCF | CYP1A2 471/4885CYP2C19 700/4885PON1 2328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.