Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313561 | 0.89 | CYP1A2 (0.38) | MAPT | |
| SCHEMBL14627275 | 0.83 | MAPT (0.33) | MAPT | |
| SCHEMBL326812 | 0.75 | PTGS2 (0.34) | MAPT | |
| SCHEMBL29545829 | 0.71 | CYP1A2 (0.34) | MAPT | |
| SCHEMBL312890 | 0.71 | CYP1A2 (0.34) | MAPT | |
| SCHEMBL312024 | 0.69 | MAPT (0.33) | MAPT | |
| SCHEMBL21409606 | 0.67 | CYP3A4 (0.52) | MAPT | |
| SCHEMBL1481477 | 0.66 | CYP2D6 (0.37) | MAPT | |
| SCHEMBL1479983 | 0.66 | TDP2 (0.37) | MAPT | |
| SCHEMBL9761249 | 0.65 | PON1 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130237719-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | FINA TECHNOLOGY, INC. (US) | 2013-09-12 | — | — | US | disclosed |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| US-8093418-B2 | Metallocenes; for production of ethylene/propylene homo-/copolymers | FINA TECHNOLOGY, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093418-B2 | Metallocenes; for production of ethylene/propylene homo-/copolymers | FINA TECHNOLOGY, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-8093418-B2 | Metallocenes; for production of ethylene/propylene homo-/copolymers | FINA TECHNOLOGY, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-7605294-B2 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7605294-B2 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-7605294-B2 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-20090076315-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED FLUORENES | FINA TECHNOLOGY, INC. (US) | 2009-03-19 | — | — | US | disclosed |
| US-20080026935-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | FINA TECHNOLOGY, INC. (US) | 2008-01-31 | — | — | US | disclosed |
| WO-2007022244-A2 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007022244-A2 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070043183-A1 | Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins | FINA TECHNOLOGY, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070043183-A1 | Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins | FINA TECHNOLOGY, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070043183-A1 | Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins | FINA TECHNOLOGY, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-7094938-B1 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2006-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237719-A1 | Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins | SFN, FANCF, B2M | MAPT 4128/4885 |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | TFDP2, ZKSCAN2, MDM4 | MAPT 2677/4885 |
| US-20120095175-A1 | PREPARATION AND USE OF TETRASUBSTITUTED FLUORENYL CATALYSTS FOR POLYMERIZATION OF OLEFINS | PYM1, SFN, FANCF | MAPT 3168/4885 |
| US-20090076315-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED FLUORENES | TFDP2, ZKSCAN2, MDM4 | MAPT 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.