Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19876662 | 0.84 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1HTR6L3MBTL1 | |
| SCHEMBL31370502 | 0.82 | HTR6 (0.36) | HSP90AA1HSP90AB1HTR6PTGS1MTNR1A | |
| SCHEMBL14304582 | 0.77 | AKR1C3 (0.47) | HTR6ALDH1A1PTGS1MTNR1AMTNR1B | |
| SCHEMBL29942639 | 0.77 | AKR1C3 (0.47) | HTR6ALDH1A1PTGS1MTNR1AMTNR1B | |
| SCHEMBL17518510 | 0.76 | CYP3A4 (0.34) | HSP90AA1HSP90AB1HTR6L3MBTL1 | |
| SCHEMBL31357981 | 0.74 | DGAT2 (0.40) | SUV39H2HTR6ALDH1A1TP53 | |
| SCHEMBL29162329 | 0.74 | HTR6 (0.40) | HTR6ALDH1A1MTNR1AMTNR1BPDE10A | |
| SCHEMBL12422250 | 0.74 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1SUV39H2ALDH1A1TP53 | |
| SCHEMBL31424127 | 0.72 | L3MBTL1 (0.39) | MTNR1AMTNR1BPDE10AL3MBTL1 | |
| SCHEMBL14605052 | 0.71 | POLB (0.42) | HSP90AA1HSP90AB1HTR6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |