Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480194 | 0.84 | KDM4E (0.57) | POLBKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL31359093 | 0.82 | ALDH1A1 (0.61) | POLBKDM4EALDH1A1GAAGLA | |
| SCHEMBL6982033 | 0.79 | ALDH1A1 (0.64) | POLBKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL15752150 | 0.79 | RECQL (0.64) | POLBKAT2AKAT2BKDM4EALDH1A1 | |
| SCHEMBL31359141 | 0.77 | MAPT (0.53) | POLBKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL31359042 | 0.75 | KMT2A (0.51) | POLBKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL31359092 | 0.75 | GCK (0.50) | POLBKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3311524 | 0.73 | ALDH1A1 (0.73) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL11985495 | 0.72 | CYP1A2 (0.67) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL31359100 | 0.72 | KMT2A (0.60) | POLBKDM4EALDH1A1SMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559464-B2 | Quinazolinone dione compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250026726-A1 | QUINAZOLINONE DIONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250026726-A1 | QUINAZOLINONE DIONE COMPOUNDS AND USES THEREOF | TNNI3, TNNT2, MYLK2 | POLB 3950/4885KAT2A 2734/4885KAT2B 3260/4885 |
| US-12559464-B2 | Quinazolinone dione compounds and uses thereof | TNNI3, TNNT2, TNNC1 | POLB 2280/4885KAT2A 2125/4885KAT2B 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.