Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293641 | 0.82 | LMNA (0.56) | ALDH1A1HPGDSMN1; SMN2CYP1A2TSHR | |
| SCHEMBL30615329 | 0.82 | LMNA (0.56) | ALDH1A1HPGDSMN1; SMN2CYP1A2TSHR | |
| SCHEMBL31359005 | 0.79 | POLB (0.57) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL30877025 | 0.79 | HPGD (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL6982894 | 0.79 | HPGD (1.00) | ALDH1A1KDM4EHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL14123133 | 0.79 | GRIN1 (0.53) | ALDH1A1AGTR1MEN1KMT2A | |
| SCHEMBL6980977 | 0.76 | PKM (0.79) | ALDH1A1KDM4EHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL24439067 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDAGTR1HSD17B10 | |
| SCHEMBL29674703 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDAGTR1HSD17B10 | |
| SCHEMBL7322530 | 0.74 | GABRA5 (0.53) | ALDH1A1KDM4EAGTR1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199530-A1 | New compounds derived from quinazoline | LES LABORATORIES SERVIER (FR) | 2003-10-23 | — | — | US | disclosed |
| EP-1346992-A1 | Quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199530-A1 | New compounds derived from quinazoline | NQO2, XDH, DRD1 | ALDH1A1 331/4885KDM4E 4217/4885HPGD 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.