Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711439 | 0.83 | TDP1 (0.54) | ALDH1A1CYP3A4NPC1RAB9ATDP1 | |
| SCHEMBL31359583 | 0.81 | CES2 (0.43) | GSK3BALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL14297444 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP3A4NPC1RAB9ACA1 | |
| SCHEMBL5781380 | 0.81 | CES2 (0.43) | GSK3BALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL5781385 | 0.81 | CES2 (0.43) | GSK3BALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL3446600 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP3A4NPC1RAB9ATDP1 | |
| SCHEMBL9418026 | 0.80 | ELANE (0.53) | ALDH1A1CYP3A4NPC1RAB9ATDP1 | |
| SCHEMBL31359582 | 0.80 | TDP1 (0.58) | ALDH1A1NPC1RAB9ACA1CA2 | |
| SCHEMBL14091072 | 0.79 | HDAC1 (0.51) | ALDH1A1CYP3A4NPC1RAB9ALMNA | |
| SCHEMBL1964826 | 0.76 | GSK3B (0.61) | GSK3BALDH1A1TPMTRAB9ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292593-B1 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2006-06-07 | — | — | EP | disclosed |
| US-6924298-B2 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | DOW AGROSCIENCES LLC (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040006108-A1 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | TISDELL FRANCIS EUGENE (US) | 2004-01-08 | — | — | US | disclosed |
| EP-1292593-A2 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | Dow AgroSciences LLC (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001098296-A2 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2001-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006108-A1 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | TARS2, TTL, TARS1 | GSK3B 2537/4885ALDH1A1 1876/4885CYP3A4 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.