Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10168708 | 1.00 | CXCR2 (0.44) | CXCR2ALDH1A1HTTGAAALOX15 | |
| SCHEMBL31361067 | 1.00 | CXCR2 (0.44) | CXCR2ALDH1A1HTTGAAALOX15 | |
| SCHEMBL10168724 | 0.88 | MAPT (0.47) | ALDH1A1HTTGAAALOX15TDP1 | |
| SCHEMBL10168705 | 0.82 | AKR1C3 (0.42) | CXCR2GAAALOX15MAPTKDM4E | |
| SCHEMBL31361085 | 0.76 | JAK2 (0.46) | ALDH1A1HTTCDK2 | |
| SCHEMBL31361068 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HTTMAPTHPGDHSD17B10 | |
| SCHEMBL31361077 | 0.76 | RAB9A (0.52) | ALDH1A1HTTGAAMAPTKDM4E | |
| SCHEMBL894648 | 0.75 | JAK2 (0.49) | ALDH1A1HTTMAPTHPGDKMT2A | |
| SCHEMBL15096265 | 0.75 | SYK (0.68) | CXCR2ALDH1A1HTTGAAALOX15 | |
| SCHEMBL21596400 | 0.73 | JAK3 (0.55) | MAPTGFERNGLY1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176820-A | Tricyclic compounds as MAT2A inhibitors | 艾立康药业股份有限公司 | 2024-12-24 | — | — | CN | disclosed |