Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361068 | 0.85 | ALDH1A1 (0.44) | RAB9AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL31361067 | 0.76 | CXCR2 (0.44) | ALDH1A1HPGDMAPTPOLBMEN1 | |
| SCHEMBL10168708 | 0.76 | CXCR2 (0.44) | ALDH1A1HPGDMAPTPOLBMEN1 | |
| SCHEMBL31361069 | 0.76 | CXCR2 (0.44) | ALDH1A1HPGDMAPTPOLBMEN1 | |
| SCHEMBL31361062 | 0.75 | POLB (0.38) | RAB9AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL28530643 | 0.74 | POLB (0.38) | RAB9AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL30544155 | 0.74 | POLB (0.38) | RAB9AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL31361070 | 0.72 | GCK (0.41) | RAB9AALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL26534099 | 0.72 | RAB9A (0.43) | RAB9AALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL2094424 | 0.70 | POLB (0.72) | ALDH1A1HPGDSMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176820-A | Tricyclic compounds as MAT2A inhibitors | 艾立康药业股份有限公司 | 2024-12-24 | — | — | CN | disclosed |