Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361266 | 0.90 | MEN1 (0.48) | MAT2AKMT2AMEN1HTTNPSR1 | |
| SCHEMBL31361448 | 0.87 | P2RX3 (0.39) | MAT2AKMT2AMEN1HTTNPSR1 | |
| SCHEMBL31361411 | 0.86 | MAT2A (0.52) | MAT2AKMT2AMEN1HTTNPSR1 | |
| SCHEMBL31361346 | 0.86 | MEN1 (0.39) | MAT2AKMT2AMEN1HTTNPSR1 | |
| SCHEMBL31361339 | 0.85 | MAT2A (0.39) | MAT2AKMT2AMEN1HTTNPSR1 | |
| SCHEMBL31361350 | 0.85 | MAT2A (0.42) | MAT2AKMT2AMEN1HTTNPSR1 | |
| SCHEMBL31361364 | 0.82 | KMT2A (0.40) | MAT2APTGDR2KMT2AMEN1HTT | |
| SCHEMBL31361311 | 0.82 | HTT (0.39) | MAT2AKMT2AMEN1HTTNPSR1 | |
| SCHEMBL31361455 | 0.81 | KMT2A (0.40) | MAT2AKMT2AMEN1HTTNPSR1 | |
| SCHEMBL31361328 | 0.81 | MAT2A (0.42) | MAT2AKMT2AMEN1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |