Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.37 |
| ▸ | LTA4H | P09960 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361266 | 0.91 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361342 | 0.88 | LTA4H (0.37) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361339 | 0.88 | MAT2A (0.39) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361448 | 0.86 | P2RX3 (0.39) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361403 | 0.86 | MAT2A (0.39) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361411 | 0.85 | MAT2A (0.52) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361350 | 0.84 | MAT2A (0.42) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361364 | 0.83 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361455 | 0.82 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2HTTNPSR1 | |
| SCHEMBL31361380 | 0.82 | NPSR1 (0.43) | MEN1KMT2ASMN1; SMN2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |