Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TGFBR1 | P36897 | 8/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230383 | 0.88 | ALDH1A1 (0.55) | MAPTALDH1A1TGFBR1PIK3CDPIK3CA | |
| SCHEMBL19783113 | 0.82 | TGFBR1 (0.49) | MAPTALDH1A1TGFBR1PIK3CDPIK3CA | |
| SCHEMBL11796387 | 0.79 | TGFBR1 (0.56) | MAPTTGFBR1PIK3CDPIK3CAPI4KA | |
| SCHEMBL3113871 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1ADORA2AADORA1PIK3CD | |
| Bromide SCHEMBL29078717 | 0.78 | TGFBR1 (0.54) | MAPTTGFBR1PIK3CDPIK3CAPI4KA | |
| SCHEMBL6440938 | 0.77 | NPC1 (0.50) | MAPTALDH1A1TGFBR1ADORA2AADORA1 | |
| SCHEMBL2174125 | 0.77 | ALDH1A1 (1.00) | MAPTALDH1A1KDM4EGLAGAA | |
| SCHEMBL15993383 | 0.77 | HSD17B10 (0.42) | MAPTALDH1A1ADORA2AADORA1KDM4E | |
| SCHEMBL31361561 | 0.76 | TGFBR1 (0.55) | MAPTTGFBR1PIK3CDPIK3CAPI4KA | |
| SCHEMBL3737029 | 0.76 | TGFBR1 (0.55) | MAPTTGFBR1PIK3CDPIK3CAPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746882-A1 | INHIBITORS OF SMNDC1 AND THEIR THERAPEUTIC USE | CeMM - Forschungszentrum für Molekulare Medizin GmbH (AT) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017207-A1 | INHIBITORS OF SMNDC1 AND THEIR THERAPEUTIC USE | CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) | 2025-01-23 | — | — | WO | disclosed |