Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361616 | 0.85 | ACACB (0.41) | TLR9RAB9ANPC1MEN1KMT2A | |
| SCHEMBL30962741 | 0.85 | PDE4A (0.43) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL31361629 | 0.82 | KMT2A (0.47) | NPC1MEN1KMT2ALMNAPDE4B | |
| SCHEMBL31361704 | 0.80 | PDE4D (0.41) | PDE4BPDE4APDE4CPDE4DEPHX2 | |
| SCHEMBL31361688 | 0.78 | RXFP1 (0.46) | NPC1MEN1KMT2ALMNAPDE4B | |
| SCHEMBL31361672 | 0.78 | PDE4A (0.43) | LMNATP53PDE4BPDE4APDE4C | |
| SCHEMBL31361675 | 0.76 | DHODH (0.46) | MEN1KMT2ALMNAPDE4BMAPT | |
| SCHEMBL31361679 | 0.76 | JAK1 (0.54) | MAPK1JAK3 | |
| SCHEMBL31361635 | 0.75 | JAK2 (0.42) | DHODHLCKEGFRSRCJAK3 | |
| SCHEMBL29037763 | 0.75 | TP53 (0.69) | TLR9RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |