Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 5/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361647 | 0.86 | ACACB (0.41) | PDE4DPDE4APDE4BPDE4CDHODH | |
| SCHEMBL30962741 | 0.84 | PDE4A (0.43) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL31361629 | 0.81 | KMT2A (0.47) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL31361692 | 0.80 | TLR9 (0.42) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL31361688 | 0.78 | RXFP1 (0.46) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL31361672 | 0.77 | PDE4A (0.43) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL31361675 | 0.75 | DHODH (0.46) | PDE4BDHODH | |
| SCHEMBL31361679 | 0.75 | JAK1 (0.54) | JAK3TYK2 | |
| SCHEMBL31361635 | 0.75 | JAK2 (0.42) | DHODHLCKEGFRSRCJAK3 | |
| SCHEMBL31361585 | 0.74 | PDE4B (0.46) | PDE4DPDE4APDE4BPDE4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |