Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361692 | 0.85 | TLR9 (0.42) | NPC1TP53SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL31361649 | 0.85 | RXFP1 (0.44) | ACACBKMT2AMAOAMAOBMAPT | |
| SCHEMBL31361647 | 0.84 | ACACB (0.41) | ACACBMAOAMAOBP2RX7 | |
| SCHEMBL31361601 | 0.75 | FLT4 (0.47) | — | |
| SCHEMBL31361585 | 0.72 | PDE4B (0.46) | NPC1TP53KMT2AMAPTMEN1 | |
| SCHEMBL30962741 | 0.71 | PDE4A (0.43) | MAPT | |
| SCHEMBL31361704 | 0.69 | PDE4D (0.41) | — | |
| SCHEMBL31361629 | 0.69 | KMT2A (0.47) | NPC1KMT2AMAPTMEN1LMNA | |
| SCHEMBL29037763 | 0.68 | TP53 (0.69) | GFERNPC1TP53SMN1; SMN2RAB9A | |
| SCHEMBL24796636 | 0.68 | ACACB (0.48) | ACACBSMN1; SMN2MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |