Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361704 | 0.86 | PDE4D (0.41) | POLBDHODHPDE4APDE4BPDE4C | |
| SCHEMBL31361649 | 0.85 | RXFP1 (0.44) | ACACBMAOAMAOBPOLBPDE4B | |
| SCHEMBL31361616 | 0.84 | ACACB (0.41) | ACACBMAOAMAOBP2RX7 | |
| SCHEMBL31361601 | 0.75 | FLT4 (0.47) | — | |
| SCHEMBL31361585 | 0.72 | PDE4B (0.46) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30962741 | 0.71 | PDE4A (0.43) | POLBDHODHPDE4APDE4BPDE4C | |
| SCHEMBL31361629 | 0.69 | KMT2A (0.47) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31361692 | 0.68 | TLR9 (0.42) | POLBDHODHPDE4APDE4BPDE4C | |
| SCHEMBL24796636 | 0.68 | ACACB (0.48) | ACACBMAOBBACE1 | |
| SCHEMBL31361688 | 0.68 | RXFP1 (0.46) | POLBPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |