Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859137 | 0.77 | TSHR (0.41) | ALDH1A1MAPTSMN1; SMN2CYP3A4TSHR | |
| SCHEMBL29525219 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL440478 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL27859136 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL397387 | 0.73 | ATM (0.50) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL2471756 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL23153879 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL22897917 | 0.72 | TSHR (0.53) | ALDH1A1MAPTCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL12348008 | 0.72 | GRM8 (0.49) | ALDH1A1MAPTSMN1; SMN2CYP3A4TSHR | |
| SCHEMBL10342981 | 0.72 | GPR35 (0.47) | ALDH1A1MAPTSMN1; SMN2CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119183452-A | LRRK2 inhibitors | 布雷宁疗法公司 | 2024-12-24 | — | — | CN | disclosed |