Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20267761 | 0.94 | KDM4E (0.53) | KDM4EPKMMAPTALDH1A1LMNA | |
| SCHEMBL30007138 | 0.85 | KDM4E (0.50) | KDM4EPKMALDH1A1LMNAESR1 | |
| SCHEMBL31575 | 0.82 | KDM4E (0.58) | KDM4EPKMMAPTALDH1A1LMNA | |
| SCHEMBL25767003 | 0.77 | ALDH1A1 (0.42) | KDM4EPKMMAPTALDH1A1LMNA | |
| SCHEMBL27634383 | 0.76 | KDM4E (0.55) | KDM4EPKMMAPTALDH1A1LMNA | |
| SCHEMBL27656855 | 0.74 | KDM4E (0.51) | KDM4EPKMMAPTALDH1A1LMNA | |
| SCHEMBL23942608 | 0.73 | MAPT (0.40) | KDM4EPKMMAPTALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL29832016 | 0.73 | KDM4E (0.51) | KDM4EPKMMAPTALDH1A1LMNA | |
| SCHEMBL255470 | 0.72 | PKM (0.62) | KDM4EPKMMAPTALDH1A1TSHR | |
| SCHEMBL21518854 | 0.72 | SMN1; SMN2 (0.42) | KDM4EPKMMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119421877-A | Substituted heterocyclic compounds as HSET inhibitors | 默克专利股份公司 | 2025-02-11 | — | — | CN | disclosed |