SCHEMBL31362992

SCHEMBL31362992

COC(=O)N(Cc1ccc(C)cc1C)NC(=O)c1c(Oc2cc(C(F)(F)F)ccn2)cnn1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CETP P11597 2/20 0.35
HCRTR1 O43613 2/20 0.34
HCRTR2 O43614 1/20 0.34
FLT1 P17948 3/20 0.33
KDR P35968 3/20 0.33
SORT1 Q99523 1/20 0.33
CCR2 P41597 2/20 0.32
PKM P14618 1/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
DGAT2 Q96PD7 1/20 0.32
KLKB1 P03952 1/20 0.32
HCK P08631 1/20 0.31
NR2C2 P49116 1/20 0.31
CCR5 P51681 1/20 0.31
RAB9A P51151 1/20 0.31
DHODH Q02127 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31363034 0.77 HTT (0.36) PKMALDH1A1GAA
SCHEMBL31362973 0.77 MAPT (0.35) PKMALDH1A1KDM4EHPGDGAA
SCHEMBL31362950 0.76 RAB9A (0.36) CCR2ALDH1A1KDM4EHPGDGAA
SCHEMBL31363015 0.74 SORT1 (0.39) HCRTR1HCRTR2FLT1KDRSORT1
SCHEMBL31362970 0.73 AKR1C3 (0.40) CCR2ALDH1A1KDM4ERAB9A
SCHEMBL31163187 0.71 LMNA (0.39) CCR2ALDH1A1KDM4EGAARAB9A
SCHEMBL31362958 0.71 SCN9A (0.36) HCRTR1HCRTR2FLT1KDRALDH1A1
SCHEMBL31363079 0.70 P2RY1 (0.38) CCR2ALDH1A1KDM4ERAB9A
SCHEMBL31363012 0.70 LMNA (0.34) ALDH1A1KDM4EGAARAB9A
SCHEMBL31362977 0.69 LMNA (0.40) ALDH1A1KDM4EHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025033011-A1 FIVE-MEMBERED HETEROARYL COMPOUND AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 日本曹達株式会社 2025-02-13 WO disclosed