SCHEMBL31363012

SCHEMBL31363012

COC(=O)N(Cc1ccc(C)cc1C)NC(=O)c1c(O)c(Cl)nn1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.34
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
POLB P06746 2/20 0.33
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
PDE4B Q07343 1/20 0.32
MAPT P10636 3/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MAPK1 P28482 1/20 0.32
FYN P06241 1/20 0.32
TAS1R3 Q7RTX0 2/20 0.31
TAS1R1 Q7RTX1 2/20 0.31
TAS1R2 Q8TE23 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALPL P05186 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31362978 0.80 ALDH1A1 (0.32) LMNARAB9ANPC1MAPTKMT2A
SCHEMBL30919473 0.77 NR3C1 (0.35) LMNARAB9APOLBNR3C1PGR
SCHEMBL30919506 0.72 POLB (0.36) RAB9ANPC1POLBMAPTALDH1A1
SCHEMBL31362973 0.72 MAPT (0.35) LMNAPOLBMAPTKMT2AMEN1
SCHEMBL31363034 0.71 HTT (0.36) LMNAMAPTKMT2AMEN1ALDH1A1
SCHEMBL31362974 0.70 CYP1A2 (0.34) LMNARAB9ANPC1POLBKMT2A
SCHEMBL31362992 0.70 CETP (0.35) RAB9AALDH1A1KDM4EGAA
SCHEMBL31363017 0.66 PYCR1 (0.42) RAB9ANPC1MAPTKMT2AMEN1
SCHEMBL31363031 0.59 L3MBTL1 (0.42) RAB9ANPC1POLBMAPTSMN1; SMN2
SCHEMBL10015983 0.58 NPC1 (0.45) RAB9ANPC1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025033011-A1 FIVE-MEMBERED HETEROARYL COMPOUND AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 日本曹達株式会社 2025-02-13 WO disclosed