Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29812082 | 0.82 | TXNRD1 (0.48) | TXNRD1ALDH1A1LMNATDP1SIRT6 | |
| SCHEMBL10911117 | 0.82 | TXNRD1 (0.48) | TXNRD1ALDH1A1LMNATDP1SIRT6 | |
| SCHEMBL28217544 | 0.82 | ALDH1A1 (0.45) | TXNRD1ALDH1A1LMNATDP1SIRT6 | |
| SCHEMBL31363712 | 0.80 | MAPT (0.45) | ALDH1A1LMNATDP1PNMT | |
| SCHEMBL6522436 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1LMNATDP1SIRT6L3MBTL1 | |
| SCHEMBL30184523 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1LMNATDP1SIRT6L3MBTL1 | |
| SCHEMBL28826257 | 0.75 | POLB (0.47) | TXNRD1ALDH1A1LMNATDP1SIRT6 | |
| SCHEMBL15823469 | 0.74 | ALDH1A1 (0.54) | ALDH1A1LMNATDP1SIRT6GAA | |
| SCHEMBL10911114 | 0.74 | ALDH1A1 (0.51) | TXNRD1ALDH1A1LMNATDP1SIRT6 | |
| SCHEMBL15824942 | 0.74 | ALDH1A1 (0.51) | ALDH1A1LMNATDP1SIRT6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |