Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29212451 | 0.77 | — | — | |
| SCHEMBL25030877 | 0.76 | — | — | |
| SCHEMBL30184473 | 0.76 | — | — | |
| SCHEMBL31304829 | 0.76 | ALDH1A1 (0.35) | LRRK2MAOAMAOB | |
| SCHEMBL31304800 | 0.74 | CA12 (0.31) | CA12CA1CA2CA9 | |
| SCHEMBL31634117 | 0.72 | — | — | |
| SCHEMBL31304823 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL31304965 | 0.71 | GPR119 (0.32) | LRRK2CA12CA1CA2CA9 | |
| SCHEMBL31634055 | 0.70 | LRRK2 (0.31) | LRRK2 | |
| SCHEMBL31634072 | 0.68 | ACHE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192307-A | Compounds targeting p53 mutations | 上海齐鲁制药研究中心有限公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |