SCHEMBL3136339

SCHEMBL3136339

O=S(=O)(Cl)c1nc2ccccc2o1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALOX15 P16050 1/20 0.45
PSMB8 P28062 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
POLB P06746 1/20 0.42
CASP6 P55212 1/20 0.42
TP53 P04637 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
PTGS2 P35354 1/20 0.41
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 4/20 0.41
HPGD P15428 3/20 0.41
PKM P14618 2/20 0.41
HCRTR1 O43613 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329398 0.82 MAPT (0.47) MAPTNPC1RAB9ALMNAGAA
SCHEMBL3137645 0.82 CA2 (0.46) MAPTNPC1RAB9ALMNAGAA
SCHEMBL544259 0.81 MAPT (0.46) MAPTNPC1RAB9ALMNAGAA
SCHEMBL329399 0.81 MAPT (0.46) MAPTNPC1RAB9ALMNAGAA
SCHEMBL305334 0.81 LMNA (0.53) MAPTNPC1RAB9ALMNAGAA
SCHEMBL31665885 0.81 MAPT (0.46) MAPTNPC1RAB9ALMNAGAA
SCHEMBL27475289 0.79 MAPT (0.44) MAPTNPC1RAB9ALMNAGAA
SCHEMBL2244849 0.78 LMNA (0.50) MAPTNPC1RAB9ALMNAGAA
SCHEMBL8232118 0.77 MAPT (0.47) MAPTNPC1RAB9ALMNAGAA
SCHEMBL15157903 0.77 MAPT (0.46) MAPTNPC1RAB9ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264026-A Method for synthesizing cyclic sulfonamide and sulfonyl olefin by mechanical light excitation 西北大学 2025-01-07 CN disclosed
EP-2643299-B1 BIPYRIDINE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OR CONDITIONS NOSCIRA SA (ES) 2016-06-22 EP disclosed
EP-2174936-B1 PNA monomer and precursor PANAGENE INC (KR) 2013-09-04 EP disclosed
EP-2174936-A1 PNA monomer and precursor Panagene, Inc. (KR) 2010-04-14 EP disclosed
EP-1501812-B1 PNA MONOMER AND PRECURSOR PANAGENE INC (KR) 2009-12-30 EP disclosed
US-7411065-B2 Peptide nucleic acid monomers: diphenylmethyl, benzyl, alkylthioalkyl, or phenylthioalkyl esters of N-(1-[4-(2-benzothiazolyl-, 2-benzoxazolyl-, 2-benzofuranyl- or 2-benzothiophenyl-sulfonyl)-3-piperazinon-1-ylcarbonylmethyl]pyrimidon-4-yl)carbamic acids PANAGENE, INC. (KR) 2008-08-12 US disclosed
US-7371860-B2 PNA monomer and precursor PANAGENE, INC. (KR) 2008-05-13 US disclosed
US-7371859-B2 Peptide nucleic acid monomers; 1-(4-(benzothiazolyl-, benzoxazolyl-, benzofuranyl-, and benzothiophenyl- sulfonyl)piperidin-3-one-1-ylcarbonylmethyl)adenines; suitable for automatic and parallel synthesis; increased yields PANAGENE, INC. (KR) 2008-05-13 US disclosed
CN-100347161-C PNA monomer and precursor PANAGENE INC (KR) 2007-11-07 CN disclosed
US-7179896-B2 Method of making PNA oligomers PANAGENE, INC. (KR) 2007-02-20 US disclosed
US-4842981-A RADIATING A COLORLESS, CHROMOGENIC COATING AND A RUPTURABLE CAPSULE CONTAINING PHOTOSENSITIVE MATERIAL; IN PRESENCE OF DEVELOPER THE MEAD CORPORATION (US) 1989-06-27 US disclosed
US-4842976-A Color image-forming process MEAD CORP. (US) 1989-06-27 US disclosed
US-4822714-A Transfer imaging system THE MEAD CORPORATION (US) 1989-04-18 US disclosed
US-4764451-A Image-forming method employing light-sensitive material containing silver halide, reducing agent, polymerizable compound and a photopolymerization initiator FUJI PHOTO FILM CO., LTD. (JP) 1988-08-16 US disclosed
US-4551407-A Transfer imaging system THE MEAD CORPORATION (US) 1985-11-05 US disclosed
US-4536463-A Imaging system THE MEAD CORPORATION (US) 1985-08-20 US disclosed
US-4440846-A Photocopy sheet employing encapsulated radiation sensitive composition and imaging process MEAD CORPORATION (US) 1984-04-03 US disclosed
US-4416966-A Capsular imaging system comprising decolorizing agent THE MEAD CORPORATION (US) 1983-11-22 US disclosed
US-4399209-A Transfer imaging system THE MEAD CORPORATION (US) 1983-08-16 US disclosed
US-4069259-A Process for preparing organic disulfides ALLIED CHEMICAL CORPORATION (US) 1978-01-17 US disclosed