Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26376249 | 0.81 | GPR119 (0.45) | PDK1PDK2PDK3PDK4GPR119 | |
| SCHEMBL29811795 | 0.81 | LMNA (0.48) | PDK1PDK2PDK3PDK4GPR119 | |
| SCHEMBL23155477 | 0.81 | LMNA (0.48) | PDK1PDK2PDK3PDK4GPR119 | |
| SCHEMBL29430876 | 0.80 | NPC1 (0.47) | PDK1PDK2PDK3PDK4GPR119 | |
| SCHEMBL23155592 | 0.80 | PDK1 (0.61) | PDK1PDK2PDK3PDK4GPR119 | |
| SCHEMBL29812028 | 0.80 | PDK1 (0.61) | PDK1PDK2PDK3PDK4GPR119 | |
| SCHEMBL2002399 | 0.80 | ALDH1A1 (0.60) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL30177475 | 0.79 | IRAK4 (0.48) | PDK1PDK2PDK3PDK4GPR119 | |
| SCHEMBL24853597 | 0.79 | IRAK4 (0.48) | PDK1PDK2PDK3PDK4GPR119 | |
| SCHEMBL23155581 | 0.79 | CNR2 (0.51) | PDK1PDK2PDK3PDK4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |