Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28269645 | 0.69 | NFKB1 (0.42) | NFKB1NFKB2RELACA1GAA | |
| SCHEMBL27991298 | 0.69 | NFKB1 (0.42) | NFKB1NFKB2RELACA1GAA | |
| SCHEMBL31363842 | 0.64 | CTSK (0.44) | CTSKNFKB1NFKB2RELACA1 | |
| SCHEMBL31363878 | 0.64 | DRD2 (0.36) | DRD2NFKB1NFKB2RELACA12 | |
| SCHEMBL4641612 | 0.63 | CTSK (0.46) | CTSKNFKB1NFKB2RELACA1 | |
| SCHEMBL4641603 | 0.63 | CTSK (0.46) | CTSKNFKB1NFKB2RELACA1 | |
| SCHEMBL4641615 | 0.63 | CTSK (0.46) | CTSKNFKB1NFKB2RELACA1 | |
| SCHEMBL12814322 | 0.63 | CTSK (0.54) | DRD2CTSKNFKB1NFKB2RELA | |
| SCHEMBL22874540 | 0.63 | NFKB1 (0.38) | NFKB1NFKB2RELACA1GAA | |
| SCHEMBL14908035 | 0.63 | CTSK (0.43) | CTSKNFKB1NFKB2RELACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |