Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177475 | 0.89 | IRAK4 (0.48) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL24853597 | 0.89 | IRAK4 (0.48) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL1186312 | 0.88 | CA2 (0.54) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL1007951 | 0.82 | GPR119 (0.49) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2002399 | 0.82 | ALDH1A1 (0.60) | KMT2AALDH1A1GAALMNAMEN1 | |
| SCHEMBL13294871 | 0.81 | KMT2A (0.61) | SMN1; SMN2KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL26376249 | 0.81 | GPR119 (0.45) | SMN1; SMN2KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL29991362 | 0.80 | GAA (0.60) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL115661 | 0.80 | GAA (0.60) | SMN1; SMN2KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL29812028 | 0.80 | PDK1 (0.61) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |