Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777113 | 0.83 | KCNN4 (0.44) | ALDH1A1CES1PDK2 | |
| SCHEMBL6489437 | 0.81 | CA1 (0.50) | ALDH1A1TSHRLMNAGAAL3MBTL1 | |
| SCHEMBL8376253 | 0.77 | HSD17B10 (0.47) | ALDH1A1TSHRGAATDP1POLB | |
| SCHEMBL2582219 | 0.75 | MEN1 (0.52) | ALDH1A1TSHRLMNAGAAPOLB | |
| SCHEMBL1201504 | 0.73 | CES2 (0.41) | HPGDCES1PDK2CA2 | |
| SCHEMBL6810664 | 0.73 | KDM4E (0.36) | ALDH1A1TSHRLMNAGAATDP1 | |
| SCHEMBL63469 | 0.72 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNAGAATDP1 | |
| SCHEMBL29441997 | 0.72 | ALDH1A1 (0.52) | ALDH1A1TSHRLMNAGAATDP1 | |
| SCHEMBL15957667 | 0.72 | TRPA1 (0.50) | ALDH1A1TSHRMAPTSMN1; SMN2PDK2 | |
| SCHEMBL8424700 | 0.71 | KDM4E (0.35) | ALDH1A1TSHRLMNAGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025022004-A2 | OPHTHALMIC LENS | CONTAMAC LIMITED (GB) | 2025-01-30 | — | — | WO | disclosed |