Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364625 | 0.85 | HPGD (0.38) | HTTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL12217744 | 0.79 | ALDH1A1 (0.43) | HTTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL23231062 | 0.77 | BRD4 (0.43) | HTTLMNAHPGDMAPK1TBXAS1 | |
| SCHEMBL31364631 | 0.76 | HPGD (0.41) | HTTKDM4ELMNAHPGDMAPK1 | |
| SCHEMBL16131514 | 0.76 | HPGD (0.44) | HTTKMT2AKDM4ELMNAHPGD | |
| SCHEMBL23231094 | 0.76 | HPGD (0.41) | HTTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL331534 | 0.76 | KEAP1 (0.44) | HTTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL23231095 | 0.73 | ALDH1A1 (0.54) | HTTKMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL23899066 | 0.72 | GAA (0.53) | HTTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL31251323 | 0.72 | GAA (0.53) | HTTMEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025020886-A1 | AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF | 浙江星浩澎博医药有限公司 | 2025-01-30 | — | — | WO | disclosed |