Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364630 | 0.85 | HTT (0.43) | HPGDHTTLMNAMAPK1NPSR1 | |
| SCHEMBL23231062 | 0.76 | BRD4 (0.43) | HPGDHTTLMNAMAPK1TBXAS1 | |
| SCHEMBL331534 | 0.75 | KEAP1 (0.44) | HPGDHTTLMNAMAPK1TBXAS1 | |
| SCHEMBL16131514 | 0.75 | HPGD (0.44) | HPGDHTTLMNAMAPK1NPSR1 | |
| SCHEMBL23231094 | 0.75 | HPGD (0.41) | HPGDHTTLMNAMAPK1TBXAS1 | |
| SCHEMBL31364631 | 0.75 | HPGD (0.41) | HPGDHTTLMNAMAPK1TBXAS1 | |
| SCHEMBL23231095 | 0.72 | ALDH1A1 (0.54) | HPGDHTTLMNAMAPK1ALDH1A1 | |
| SCHEMBL27077794 | 0.72 | NPBWR1 (0.54) | — | |
| SCHEMBL331783 | 0.70 | GAA (0.59) | HTTLMNANPSR1ALDH1A1MEN1 | |
| SCHEMBL332668 | 0.68 | NPC1 (0.51) | HPGDHTTLMNAMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025020886-A1 | AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF | 浙江星浩澎博医药有限公司 | 2025-01-30 | — | — | WO | disclosed |