Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 8/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364640 | 0.90 | AURKA (0.42) | AURKARPS6KB1AURKBEGFRATR | |
| SCHEMBL31364671 | 0.77 | JAK2 (0.38) | AURKARPS6KB1AURKBEGFRDYRK1A | |
| SCHEMBL31364639 | 0.77 | AURKA (0.37) | AURKARPS6KB1AURKBEGFR | |
| SCHEMBL31364650 | 0.69 | JAK2 (0.48) | EGFRDYRK1A | |
| SCHEMBL4438011 | 0.66 | ATF1 (0.42) | CACNA1HCACNA1BCACNA1CATRSTK17B | |
| SCHEMBL21397386 | 0.66 | LCK (0.43) | ATRSTK17BSTK17AGSK3BDYRK1A | |
| SCHEMBL29891274 | 0.66 | LCK (0.43) | ATRSTK17BSTK17AGSK3BDYRK1A | |
| SCHEMBL18805591 | 0.65 | ATR (0.45) | AURKBEGFRATRGSK3BDYRK1A | |
| SCHEMBL29400652 | 0.65 | ATR (0.45) | AURKBEGFRATRGSK3BDYRK1A | |
| SCHEMBL22028997 | 0.65 | XPO1 (0.51) | CACNA1HCACNA1BCACNA1CATRGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025020886-A1 | AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF | 浙江星浩澎博医药有限公司 | 2025-01-30 | — | — | WO | disclosed |