Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532476 | 0.85 | LMNA (0.41) | LMNAPOLBSMN1; SMN2GBA2HRH2 | |
| SCHEMBL21358300 | 0.82 | SMN1; SMN2 (0.43) | LMNAPOLBSMN1; SMN2GBA2HRH2 | |
| SCHEMBL31282074 | 0.81 | LMNA (0.44) | LMNAPOLBSMN1; SMN2GBA2HRH2 | |
| SCHEMBL23859720 | 0.80 | LMNA (0.49) | LMNAPOLBSMN1; SMN2GBA2HRH2 | |
| SCHEMBL30898345 | 0.77 | GPR119 (0.44) | SMN1; SMN2GPR119EPHX2 | |
| SCHEMBL18639389 | 0.77 | LMNA (0.46) | LMNAPOLBSMN1; SMN2GBA2HRH2 | |
| SCHEMBL21798675 | 0.73 | LMNA (0.50) | LMNAPOLBSMN1; SMN2GBA2HRH2 | |
| SCHEMBL16230841 | 0.72 | LMNA (0.56) | LMNAPOLBSMN1; SMN2GBA2HRH2 | |
| SCHEMBL21358383 | 0.72 | SMN1; SMN2 (0.49) | LMNAPOLBSMN1; SMN2GBA2HRH2 | |
| SCHEMBL23091753 | 0.72 | POLB (0.49) | LMNAPOLBSMN1; SMN2HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654326-A | Novel heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2025-03-18 | — | — | CN | disclosed |