Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.52 |
| ▸ | CMA1 | P23946 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022691 | 0.89 | HDAC3 (0.48) | CTSSCTSKCMA1HDAC3HDAC4 | |
| SCHEMBL8088239 | 0.83 | ALOX15 (0.53) | CTSSCTSKHDAC3HDAC4HDAC1 | |
| SCHEMBL8228460 | 0.79 | HDAC3 (0.48) | CTSSCTSKHDAC3HDAC4HDAC1 | |
| SCHEMBL8086699 | 0.79 | CTSL (0.58) | CTSSCTSKCTSLPOLBACE | |
| SCHEMBL23042492 | 0.78 | PTPRB (0.42) | CTSSCTSKCMA1HDAC3HDAC4 | |
| SCHEMBL13093577 | 0.77 | HDAC3 (0.53) | CTSSCTSKCMA1HDAC3HDAC4 | |
| SCHEMBL2108343 | 0.77 | CTSS (0.68) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL2108340 | 0.77 | CTSS (0.68) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL15275068 | 0.76 | PTPN1 (0.58) | CTSSCTSKHDAC3HDAC4HDAC1 | |
| SCHEMBL12616773 | 0.76 | HDAC3 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051283-A1 | THERAPEUTIC COMPOUNDS AND METHODS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051283-A1 | THERAPEUTIC COMPOUNDS AND METHODS | EIF2AK2, SARS1, REN | CTSS 1617/4885CTSK 3060/4885CMA1 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.