Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148516 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA2CHRNA7 | |
| Hydrochloric Acid SCHEMBL53199 | 0.98 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA2CHRNA7 | |
| Hydrochloric Acid SCHEMBL53425 | 0.98 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA2CHRNA7 | |
| SCHEMBL12733200 | 0.85 | CHRNB2 (0.52) | CHRNB2CHRNA4CHRNB4CHRNA2CHRNA7 | |
| SCHEMBL9600234 | 0.75 | PRCP (0.57) | CHRNB2CHRNA4HTR2C | |
| SCHEMBL31374586 | 0.75 | PRCP (0.57) | CHRNB2CHRNA4HTR2C | |
| SCHEMBL31374588 | 0.75 | PRCP (0.57) | CHRNB2CHRNA4HTR2C | |
| SCHEMBL18322101 | 0.70 | PNMT (0.41) | HTR2AHTR2CHTR2B | |
| SCHEMBL3819190 | 0.68 | CHRNB2 (0.38) | CHRNB2CHRNA4CHRNB4CHRNA2CHRNA7 | |
| Hydrochloric Acid SCHEMBL3134497 | 0.67 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNB4CHRNA2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076011-A1 | Enantiomer-Pure Hexahydro-Pyrrolocyclopenta-Pyridine Derivatives | BINDER, EVA (AT) | 2010-03-25 | — | — | US | disclosed |
| EP-1740585-B1 | ENANTIOMER-PURE HEXAHYDROPYRROLOCYCLOPENTAPYRIDINE DERIVATIVES | BINDER EVA (AT) | 2009-08-19 | — | — | EP | disclosed |
| EP-1740585-A1 | ENANTIOMER-PURE HEXAHYDRO- PYRROLOCYCLOPENTA- PYRIDINE DERIVATIVES | Binder, Eva HF (AT) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105800-A1 | ENANTIOMER-PURE HEXAHYDRO- PYRROLOCYCLOPENTA- PYRIDINE DERIVATIVES | BINDER, EVA (AT) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076011-A1 | Enantiomer-Pure Hexahydro-Pyrrolocyclopenta-Pyridine Derivatives | FFAR3, FFAR2, FFAR1 | CHRNB2 680/4885CHRNA4 302/4885CHRNB4 575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.