Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31367611 | 0.96 | NR4A2 (0.54) | NR4A2TMIGD3ADORA3ALDH1A2ALDH1A3 | |
| SCHEMBL31367545 | 0.96 | NR4A2 (0.57) | NR4A2TMIGD3ADORA3ALDH1A2ALDH1A3 | |
| SCHEMBL31367521 | 0.90 | ALDH1A3 (0.52) | NR4A2TMIGD3ADORA3ALDH1A2ALDH1A3 | |
| SCHEMBL31367461 | 0.90 | ALDH1A3 (0.52) | NR4A2TMIGD3ADORA3ALDH1A2ALDH1A3 | |
| SCHEMBL31367450 | 0.90 | ALDH1A3 (0.52) | NR4A2TMIGD3ADORA3ALDH1A2ALDH1A3 | |
| SCHEMBL31367612 | 0.82 | BCAT2 (0.55) | TMIGD3ADORA3ALDH1A2ALDH1A3ALDH1A1 | |
| SCHEMBL31367607 | 0.82 | ALDH1A3 (0.63) | TMIGD3ADORA3ALDH1A2ALDH1A3ALDH1A1 | |
| SCHEMBL31367623 | 0.82 | MAPT (0.52) | ALDH1A2ALDH1A3ALDH1A1ADORA2AADORA1 | |
| SCHEMBL31367554 | 0.82 | ALDH1A3 (0.49) | ADORA3ALDH1A2ALDH1A3ALDH1A1ADORA2A | |
| SCHEMBL31367509 | 0.81 | BCAT2 (0.56) | TMIGD3ADORA3ALDH1A2ALDH1A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735442-A1 | IMIDAZO[1,2-alpha]PYRIDINE COMPOUNDS FOR USE IN TREATING CANCER AND INFLAMMATORY DISEASES AND METHODS TO PREPARE SAID COMPOUNDS | Theranib Inc. (CA) | 2026-05-06 | — | — | EP | claimed |
| US-20250011322-A1 | MEDICAL COMPOUND FOR THE INHIBITION OF ALDEHYDE DEHYDROGENASE SUBTYPE 1A | THERANIB INC. (CA) | 2025-01-09 | — | — | US | claimed |
| EP-4735442-A1 | IMIDAZO[1,2-alpha]PYRIDINE COMPOUNDS FOR USE IN TREATING CANCER AND INFLAMMATORY DISEASES AND METHODS TO PREPARE SAID COMPOUNDS | Theranib Inc. (CA) | 2026-05-06 | — | — | EP | disclosed |
| US-20250011322-A1 | MEDICAL COMPOUND FOR THE INHIBITION OF ALDEHYDE DEHYDROGENASE SUBTYPE 1A | THERANIB INC. (CA) | 2025-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250011322-A1 | MEDICAL COMPOUND FOR THE INHIBITION OF ALDEHYDE DEHYDROGENASE SUBTYPE 1A | ALDH2, ALDH3A1, ALDH1A1 | NR4A2 841/4885TMIGD3 2337/4885ADORA3 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.