Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31367963 | 0.85 | MAPT (0.68) | MAPTMEN1KMT2APOLBCYP3A4 | |
| SCHEMBL11403258 | 0.83 | MAPT (0.66) | MAPTMEN1KMT2APOLBCYP3A4 | |
| SCHEMBL11855734 | 0.81 | GAA (0.56) | MEN1KMT2APOLBPIK3CBPIK3CA | |
| SCHEMBL23572480 | 0.77 | MEN1 (0.62) | MEN1KMT2APOLBPIK3CBPIK3CA | |
| SCHEMBL23572365 | 0.77 | MEN1 (0.62) | MEN1KMT2APOLBPIK3CBPIK3CA | |
| SCHEMBL14547699 | 0.74 | XDH (0.54) | MAPTMEN1KMT2APOLBPIK3CB | |
| SCHEMBL5381034 | 0.74 | HSD17B10 (0.58) | MEN1KMT2APOLBPIK3CBPIK3CA | |
| SCHEMBL11679829 | 0.72 | TSHR (0.54) | MAPTMEN1KMT2APOLBPIK3CB | |
| SCHEMBL26130480 | 0.70 | PIK3CB (0.43) | MAPTMEN1KMT2APOLBPIK3CB | |
| SCHEMBL497431 | 0.70 | DCTPP1 (0.48) | MEN1KMT2APOLBPIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092051-A1 | NLRP3 MODULATORS AND USE THEREOF | Bioentropy Inc. (US) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092051-A1 | NLRP3 MODULATORS AND USE THEREOF | NLRP3, NLRP1, NOD1 | MAPT 385/4885MEN1 3389/4885KMT2A 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.