Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064847 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ARMAPK1KDM4EKDM6B | |
| SCHEMBL30800091 | 0.82 | ALDH1A1 (0.54) | ALDH1A1ARMAPK1KDM4EKDM6B | |
| SCHEMBL2643688 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL70350 | 0.79 | KDM4E (0.62) | ALDH1A1ARMAPK1KDM4EKDM6B | |
| SCHEMBL30065796 | 0.79 | KDM4E (0.62) | ALDH1A1ARMAPK1KDM4EKDM6B | |
| SCHEMBL163424 | 0.79 | ALDH1A1 (0.51) | ALDH1A1ARMAPK1KDM4EKDM6B | |
| SCHEMBL850841 | 0.79 | ALDH1A1 (0.51) | ALDH1A1ARMAPK1KDM4EKDM6B | |
| SCHEMBL131790 | 0.79 | ALDH1A1 (0.51) | ALDH1A1ARMAPK1KDM4EKDM6B | |
| SCHEMBL1336313 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ARMAPK1KDM4EKDM6B | |
| SCHEMBL2642557 | 0.78 | KDR (0.46) | ALDH1A1KDM4EKDM4CMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739685-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | Janssen Pharmaceutica NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008061-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-09 | — | — | WO | disclosed |