SCHEMBL1336313

SCHEMBL1336313

COC(=O)c1cc(N)ccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
GAA P10253 2/20 0.47
AR P10275 1/20 0.46
MAPK1 P28482 2/20 0.44
KDM4E B2RXH2 4/20 0.44
KDM6B O15054 1/20 0.44
KDM5C P41229 1/20 0.44
KDM4C Q9H3R0 1/20 0.44
KDM2A Q9Y2K7 1/20 0.44
KDM3A Q9Y4C1 1/20 0.44
LCK P06239 1/20 0.43
CFTR P13569 1/20 0.42
GLA P06280 1/20 0.42
MAPT P10636 2/20 0.41
PKM P14618 2/20 0.41
ACACB O00763 1/20 0.41
ROCK1 Q13464 1/20 0.41
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
PDE5A O76074 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31345624 0.98 ALDH1A1 (0.49) ALDH1A1GAAARMAPK1KDM4E
SCHEMBL30800091 0.82 ALDH1A1 (0.54) ALDH1A1ARMAPK1KDM4EKDM6B
SCHEMBL31538151 0.82 KDM4C (0.38) ALDH1A1GAAKDM4EKDM4CMAPT
SCHEMBL31116587 0.82 KDM4C (0.38) ALDH1A1GAAKDM4EKDM6BKDM5C
SCHEMBL23461548 0.82 ALDH1A1 (0.41) ALDH1A1GAAARMAPK1KDM4E
SCHEMBL3882564 0.81 GABRG2 (0.45) ARGABRPGABRDGABRA1GABRB1
SCHEMBL3062909 0.81 ALDH1A1 (0.50) ALDH1A1MAPK1KDM4EMAPTGABRP
SCHEMBL3407841 0.80 ALDH1A1 (0.47) ALDH1A1MAPTCYP3A4
SCHEMBL163424 0.79 ALDH1A1 (0.51) ALDH1A1ARMAPK1KDM4EKDM6B
SCHEMBL131790 0.79 ALDH1A1 (0.51) ALDH1A1ARMAPK1KDM4EKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119639330-B Preparation process of waterproof coating for roads and bridges 平原县农村公路发展中心 2025-06-13 CN claimed
CN-119639330-A Preparation process of waterproof coating for roads and bridges 平原县农村公路发展中心 2025-03-18 CN claimed
US-20260144743-A1 COMPOUNDS TMEM16A LIMITED (GB) 2026-05-28 US disclosed
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors MISSION THERAPEUTICS LIMITED (GB) 2026-05-26 US disclosed
WO-2026103316-A1 TETRAHYDROFURAN-FORMAMIDE SODIUM CHANNEL MODULATOR AND USE THEREOF IN MEDICINE 嘉兴安帝康生物科技有限公司 2026-05-21 WO disclosed
WO-2026098709-A1 DEUTERATED TETRAHYDROFURAN NAV1.8 INHIBITOR AND USE THEREOF 广州楷石医药有限公司 2026-05-15 WO disclosed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 EP disclosed
US-12612383-B2 Polysubstituted pyrrolidine derivative, preparation method therefor and use thereof SHANGHAI WENNAI THERAPEUTICS CO., LTD. (CN) 2026-04-28 US disclosed
EP-4003977-B1 PYRIDINE DERIVATIVES AS CALCIUM-ACTIVATED CHLORIDE CHANNEL MODULATORS TMEM16A LTD (GB) 2026-04-15 EP disclosed
EP-4714435-A2 SOLID DOSAGE FORMS AND DOSING REGIMENS COMPRISING (2R,3S,4S,5R)-4-[[3-(3,4-DIFLUORO-2-METHOXY-PHENYL)-4,5-DIMETHYL-5-(TRIFLUOROMETHYL) TETRAHYDROFURAN-2-CARBONYL]AMINO]PYRIDINE-2-CARBOXAMIDE Vertex Pharmaceuticals Incorporated (US) 2026-03-25 EP disclosed
EP-4699655-A2 COMPOUNDS TMEM16A LIMITED (GB) 2026-02-25 EP disclosed
US-20030114674-A1 2-Hydroxy-mutilin carbamate derivatives for antibacterial use SMITHKLINE BEECHAM P.L.C. (GB) 2003-06-19 US disclosed
EP-1268443-A1 2-HYDROXY-MUTILIN CARBAMATE DERIVATIVES FOR ANTIBACTERIAL USE SmithKline Beecham p.l.c. (GB) 2003-01-02 EP disclosed
CN-1374960-A novel integrin receptor antagonists BASF AG (DE) 2002-10-16 CN disclosed
CN-1355811-A Integrain receptor antagaonists BASF AG (DE) 2002-06-26 CN disclosed
WO-2001074788-A1 2-HYDROXY-MUTILIN CARBAMATE DERIVATIVES FOR ANTIBACTERIAL USE SMITHKLINE BEECHAM PLC (GB) 2001-10-11 WO disclosed
US-4746653-A ANTAGONISTS OF N-METHYL-D-ASPARTATE SENSITIVE EXCITATORY AMINO ACID RECEPTOR; TREATMENT OF MUSCULAR SPASMS, CONVULSIVE DISORDERS AND ANXIETY CIBA-GEIGY CORPORATION (US) 1988-05-24 US disclosed
EP-0010770-B1 4-PYRIDYL UREAS OR THIOUREAS SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND PLANT GROWTH REGULANTS CONTAINING THEM Shudo, Koichi, Prof. Dr. (JP) 1982-07-07 EP disclosed
US-4279639-A N-(2-Substituted-4-pyridyl)ureas and thioureas as well as plant growth regulators containing same, and method for using compounds as plant growth regulators Okamoto, Toshihiko (JP) 1981-07-21 US disclosed
EP-0010770-A1 4-Pyridyl ureas or thioureas substituted in position 2, process for their preparation and plant growth regulants containing them Shudo, Koichi, Prof. Dr. (JP) 1980-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114674-A1 2-Hydroxy-mutilin carbamate derivatives for antibacterial use MSH6, MSH2, PMS2 ALDH1A1 1967/4885GAA 798/4885AR 4819/4885
US-20260144743-A1 COMPOUNDS CACNA1E, TMEM109, CACNA1C ALDH1A1 1592/4885GAA 1568/4885AR 1904/4885
US-12637426-B2 1-cyano-pyrrolidine compounds as USP30 inhibitors USP30, USP1, USP10 ALDH1A1 1185/4885GAA 2633/4885AR 3284/4885
US-12612383-B2 Polysubstituted pyrrolidine derivative, preparation method therefor and use thereof SCN8A, SCN11A, TRPV1 ALDH1A1 2204/4885GAA 3309/4885AR 3035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.