Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524408 | 0.85 | PTPN1 (0.46) | ALDH1A1MAPTHPGDPTPN1KDM4E | |
| SCHEMBL29451101 | 0.84 | CFTR (0.47) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6316181 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL27587157 | 0.79 | PTPN1 (0.44) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL5934445 | 0.79 | HNF4A (0.54) | PTPN1HNF4ACYP2C8FOLH1FABP4 | |
| SCHEMBL2174123 | 0.78 | HNF4A (0.58) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7211572 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL2805234 | 0.77 | ACLY (0.46) | ALDH1A1PTPN1HNF4ACYP2C8FOLH1 | |
| SCHEMBL28022356 | 0.77 | PDK2 (0.45) | ALDH1A1PTPN1HNF4ACYP2C8FOLH1 | |
| SCHEMBL28615493 | 0.77 | PTPN1 (0.43) | ALDH1A1MEN1KMT2AMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823106-A | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114144520-B | Enhanced nucleic acid polymerization by aromatic compounds | 豪夫迈·罗氏有限公司 | 2024-12-13 | — | — | CN | disclosed |