SCHEMBL3136937

SCHEMBL3136937

C=C(C)C(=O)OCc1ccc(SC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
RAB9A P51151 2/20 0.42
HTT P42858 2/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 4/20 0.41
SLC6A4 P31645 2/20 0.40
TSHR P16473 2/20 0.38
ACACB O00763 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ATM Q13315 1/20 0.37
PAX8 Q06710 1/20 0.37
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
EPHX2 P34913 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
MMP12 P39900 1/20 0.36
MMP13 P45452 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254038 0.88 ALDH1A1 (0.50) HTTALDH1A1TSHRMEN1KMT2A
SCHEMBL10172754 0.82 ALDH1A1 (0.60) KDM4EMAPTSMN1; SMN2RAB9AHTT
SCHEMBL24019226 0.82 ALDH1A1 (0.46) MAPTRAB9AHTTNPC1ALDH1A1
SCHEMBL92326 0.82 MEN1 (0.53) KDM4EHTTALDH1A1TSHRMEN1
SCHEMBL15944747 0.82 ALDH1A1 (0.46) KDM4EHTTALDH1A1TSHRMEN1
SCHEMBL16125663 0.82 ALDH1A1 (0.46) MAPTRAB9AHTTNPC1ALDH1A1
SCHEMBL17791311 0.82 ALDH1A1 (0.46) KDM4EHTTALDH1A1TSHRMEN1
SCHEMBL10720993 0.81 ALDH1A1 (0.44) KDM4EMAPTHTTALDH1A1TSHR
SCHEMBL148297 0.81 MAOB (0.47) MAPTRAB9ANPC1ALDH1A1TSHR
SCHEMBL9554958 0.81 ALDH1A1 (0.44) HTTALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930938-A Light-cured resin with adjustable refractive index, preparation method thereof and application thereof in tissue embedding 江苏博赛孚医疗科技有限公司 2025-05-06 CN claimed
CN-119930938-A Light-cured resin with adjustable refractive index, preparation method thereof and application thereof in tissue embedding 江苏博赛孚医疗科技有限公司 2025-05-06 CN disclosed
US-11649401-B2 Quantum dot-containing material, method of preparing the same, and optical member and apparatus including the quantum dot-containing material SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-11649401-B2 Quantum dot-containing material, method of preparing the same, and optical member and apparatus including the quantum dot-containing material SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-20210009893-A1 QUANTUM DOT-CONTAINING MATERIAL, METHOD OF PREPARING THE SAME, AND OPTICAL MEMBER AND APPARATUS INCLUDING THE QUANTUM DOT-CONTAINING MATERIAL SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-14 US disclosed
EP-2139878-A2 HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF BASF SE (DE) 2010-01-06 EP disclosed
WO-2008101806-A2 HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF BASF SE (CH) 2008-08-28 WO disclosed
WO-2008101806-A2 HIGH REFRACTIVE INDEX MONOMERS, COMPOSITIONS AND USES THEREOF BASF SE (CH) 2008-08-28 WO disclosed
US-20080200582-A1 High refractive index monomers, compositions and uses thereof CIBA CORP. 2008-08-21 US disclosed
US-20080200582-A1 High refractive index monomers, compositions and uses thereof CIBA CORP. 2008-08-21 US disclosed
US-20080200582-A1 High refractive index monomers, compositions and uses thereof CIBA CORP. 2008-08-21 US disclosed