SCHEMBL31369476

SCHEMBL31369476

CN(Cc1ccccc1)C[C@H](N)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.55
PKM P14618 1/20 0.55
PTGS1 P23219 1/20 0.55
XIAP P98170 1/20 0.55
SLC7A5 Q01650 1/20 0.55
CARM1 Q86X55 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
PRMT8 Q9NR22 1/20 0.49
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
SLC1A1 P43005 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31323977 1.00 ALPI (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL20400891 0.82 ALPI (0.58) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL20400893 0.82 ALPI (0.58) ALPIPKMPTGS1XIAPSLC7A5
Cadaverine Tartrate SCHEMBL28556768 0.81 MEN1 (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL25345635 0.81 KDM4E (0.52) CARM1PRMT6PRMT8KDM4EMEN1
SCHEMBL7648267 0.81 KDM4E (0.52) CARM1PRMT6PRMT8KDM4EMEN1
SCHEMBL21054744 0.80 SIGMAR1 (0.54) CARM1PRMT6PRMT8MEN1KMT2A
Hydrochloric Acid SCHEMBL7043275 0.80 KDM4A (0.50) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL209926 0.80 SIGMAR1 (0.54) CARM1PRMT6PRMT8MEN1KMT2A
SCHEMBL24829559 0.79 ALDH1A1 (0.50) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 ALPI 4682/4885PKM 3898/4885PTGS1 4090/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.