SCHEMBL313697

SCHEMBL313697

CC(C)(Cc1ccccc1)O[SiH3]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.52
TAAR1 Q96RJ0 1/20 0.52
CYP2D6 P10635 2/20 0.48
LMNA P02545 1/20 0.48
TRPA1 O75762 1/20 0.42
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP1A2 P05177 2/20 0.40
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
MMP8 P22894 1/20 0.38
TSHR P16473 1/20 0.37
CYP3A4 P08684 2/20 0.37
ALDH1A1 P00352 1/20 0.37
FDPS P14324 1/20 0.36
CTSK P43235 1/20 0.36
CALM1 P0DP23 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28191686 0.90 SLC6A2 (0.44) SLC6A2TAAR1CYP2D6LMNATRPA1
SCHEMBL3482082 0.82 SLC6A2 (0.52) SLC6A2TAAR1CYP2D6LMNATRPA1
SCHEMBL3385591 0.81 SLC6A2 (0.56) SLC6A2TAAR1CYP2D6LMNATRPA1
SCHEMBL1157985 0.81 SLC6A2 (0.56) SLC6A2TAAR1CYP2D6LMNATRPA1
SCHEMBL27101346 0.80 FFAR1 (0.38) SLC6A2TAAR1CYP2D6LMNACYP2C9
SCHEMBL3337788 0.80 KDM4E (0.49) CYP2D6LMNACYP2C9CYP2C19CYP1A2
SCHEMBL8953995 0.80 CYP3A4 (0.42) SLC6A2TAAR1CYP2D6LMNACYP2C9
SCHEMBL3481814 0.80 AGXT (0.40) SLC6A2TAAR1CYP2D6LMNACYP2C9
SCHEMBL872871 0.79 SLC6A2 (0.54) SLC6A2TAAR1CYP2D6LMNATRPA1
SCHEMBL964291 0.78 ALDH1A1 (0.39) SLC6A2TAAR1CYP2D6LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 721 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12331164-B2 Curable siloxane resin composition KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-06-17 US claimed
CN-114920623-B CO (carbon monoxide) 2 Method for preparing methanol by hydrogenation 太原工业学院 2023-09-01 CN claimed
US-20230078587-A1 CURABLE SILOXANE RESIN COMPOSITION KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-03-16 US claimed
CN-110520434-B Method for preparing arylalkoxysilanes by dehydrogenative silylation 美国陶氏有机硅公司 2022-08-23 CN claimed
CN-110734552-B Preparation method of high-purity silicon carbide polycrystalline powder source precursor 哈尔滨工业大学 2021-12-14 CN claimed
EP-3609900-B1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION DOW SILICONES CORP (US) 2021-02-17 EP claimed
CN-109608640-B High molecular weight MQ silicon resin and synthesis method and application thereof 浙江新安化工集团股份有限公司 2020-09-29 CN claimed
US-20200123181-A1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION DOW SILICONES CORP (US) 2020-04-23 US claimed
EP-3609900-A1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION Dow Silicones Corporation (US) 2020-02-19 EP claimed
CN-110734552-A Preparation method of high-purity silicon carbide polycrystalline powder source precursors 哈尔滨工业大学 2020-01-31 CN claimed
US-20050215072-A1 Method and system for treating a dielectric film TOKYO ELECTRON LIMITED (JP) 2005-09-29 US claimed
EP-1545734-A1 METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA DOW CORNING CORPORATION (US) 2005-06-29 EP claimed
US-20050029195-A1 Method of separating components in a sample using silane-treated silica filter media DOW CORNING CORPORATION 2005-02-10 US claimed
US-20040259094-A1 Method of attachment of a biomolecule to a solid surface GE HEALTHCARE UK LIMITED (GB) 2004-12-23 US claimed
US-20040211724-A1 Method of separating components in a sample using silane-treated silica filter media DOW CORNING CORPORATION 2004-10-28 US claimed
EP-1459067-A2 METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE Amersham Biosciences UK Limited (GB) 2004-09-22 EP claimed
EP-1436018-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2004-07-14 EP claimed
WO-2004041401-A1 METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA DOW CORNING CORPORATION (US) 2004-05-21 WO claimed
WO-2003026717-A1 NITRIC OXIDE-RELEASING COATED MEDICAL DEVICES AND METHOD OF PREPARING SAME THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2003-04-03 WO claimed
WO-2003027677-A2 METHOD OF ATTACHMENT OF A BIOMOLECULE TO A SOLID SURFACE AMERSHAM BIOSCIENCES UK LIMITED (GB) 2003-04-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200123181-A1 METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION DHPS, ALK, BCR SLC6A2 3356/4885TAAR1 1891/4885CYP2D6 183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.